Efficacy of social cognition and interaction training in outpatients with schizophrenia spectrum disorders: randomized controlled trial

Efficacy of social cognition and interaction training in outpatients with schizophrenia spectrum disorders: randomized controlled trial

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Given the relationship between social cognition and functional outcome in schizophrenia, a number of social cognitive interventions have been developed, including Social Cognition Interaction Training (SCIT), a group-based, comprehensive, manualized intervention.In the current trial, we examined SCIT efficacy as well as potential moderators of treatment effects.Fifty-one outpatients were randomized to SCIT or a wait-list-control (WLC), with assessments of social cognition, neurocognition, self-report, symptoms, and functioning conducted at baseline and end of the active Longboards phase.Relative to WLC, we did not find significant improvements for SCIT on neurocognition, social cognition, self-report, or symptoms, though there was a trend-level, medium effect favoring the SCIT condition on interpersonal and instrumental role function.Post-hoc analyses indicated that baseline neurocognition did not impact degree of social cognitive or functional change.

Shorter duration of illness was significantly associated with better post-training neurocognition and self-esteem and, at trend-level with better symptoms and social functioning.We discuss the importance of 2 Piece Sleeper Sectional with Chaise outcome measure selection and the need for continued evaluation of potential treatment moderators in order to better match people to existing treatments.Clinical trial registration: Clinicaltrials.gov, Identifier NCT00587561.